Fetal Growth And Gestational Age Prediction By Machine Learning

Recurrent pregnancy loss was defined as two or more first trimester pregnancy losses18. All pregnant women were discharged from the Reproductive Medicine clinic between 10 and 11 weeks of gestation. Pregnancy outcome was determined through the evaluation of hospital medical records.

This guideline was written using language that places women at the centre of care. That said, the SOGC is committed to respecting the rights of all people–including transgender, gender non-binary, and intersex people–for whom the guideline may apply. We encourage healthcare providers to engage in respectful conversation with patients regarding their gender identity as a critical part of providing safe and appropriate care. The values, beliefs and individual needs of each patient and their family should be sought and the final decision about the care and treatment options chosen by the patient should be respected. Fetal ossification centers as predictors of gestational age in normal and abnormal pregnancies. Assessment of gestational age by ultrasonic measurement of the femur length.

However, the choice of dating formula might influence dating accuracy, as these formulae have been developed from studies that differed both in the study population and study design . The error and bias due to the choice of dating formula need to be quantitatively studied to estimate the rate of PTB in a specific population . In addition to its public health importance, accurate dating is essential for clinical decision making during the antenatal period, such as scheduling monitoring visits and recommending appropriate antenatal care .

How accurate are ultrasounds in determining gestational age?

The most accurate way to determine gestational age is using the first day of the woman’s last menstrual period and confirming this gestational age with the measurement from an ultrasound exam. LMP overestimates GA by 3 days compared to USG-Hadlock method, and only half of the preterm birth were classified correctly by both these methods. CRL-based USG method is the best for GA estimation in the first trimester, and the addition of clinical and demographic features does not improve its accuracy. Garbhini-GA1 formula is an Indian-population based formula for estimating GA in the first trimester based on CRL as the prime parameter. It has better sensitivity than the more commonly used Hadlock formula in estimating the PTB rate. Our results reinforce the need to develop population-specific GA formulae.

Most women do not know the exact date of conception because it can be challenging to know exactly when ovulation occurs. Thus, their conception date is merely an estimate based on the first day of their last period. To address the truncation problem , we supplemented observations simulated from Hadlock distribution. While it is possible that the supplemented data points from the Hadlock formula could be different from our population data, since CRL is not measured beyond 14 weeks as standard clinical practice, this is the best possible way to address this issue.


Accuracy of gestational age estimation by means of fetal crown- rump length measurement. Comparison of the accuracy of gestational age estimation from fetal heart rate and crown-rump length. Clinical implications of intra- and interobserver reproducibility of transvaginal sonographic measurement of gestational sac and crown-rump length at 6-9 weeks’ gestation. Amniocentesis for fetal lung maturity is not recommended as a routine component of decision making when considering delivery in a woman with a suboptimally dated pregnancy. To make matters worse, 10%-45% of pregnant women are unable to offer reliable information about their LMP, and 18% of women with specific menstrual dates may have significant variations between menstrual and ultrasonographic timings. Ballard J.L., Novak K.K., Driver M. A simplified score for assessment of fetal maturation of newly born infants.

The earlier in gestation that the prenatal ultrasound is performed, the greater the validity that the gestational age estimates for all racial and ethnic groups becomes. When reviewing mortality rates for infants born at the limit of viability, attention to the denominator used to calculate mortality rates at the limit of viability is important (Allen et al., 1993; Evans and Levene, 2001). Many tertiary-care NICUs report birth weight- and gestational age-specific mortality rates that use the number of infants admitted to the NICU as the denominator.

& Secher, N. J. Bias in studies of preterm and postterm delivery due to ultrasound assessment of gestational age. Schematic of training process for multiple ultrasound standard plane-based gestational age estimation. Pre-trained models are based on single standard plane images trained with Consistent Rank Logit Loss. HC Head Circumference; AC Abdominal Circumference; FL Femur Length; GA Gestational Age. The long-term effects of IUGR and its adaptive mechanisms on fetal brain development and health and functioning as an adult are not well understood and need to be studied further. Adverse intrauterine circumstances can overwhelm adaptive mechanisms and lead to organ injury and death.

Differentiating the bladder from the uterus can be done easily by looking at the thickness of the wall. The rectum will be the most posterior circular structure, on pelvic ultrasound, with either an anechoic or isoechoic center on the exam. Traditionally, determining the first day of the LMP is the first step in establishing the EDD. It has been reported that approximately one half of women accurately recall their LMP (2–4). In one study, 40% of HongKongCupid the women randomized to receive first-trimester ultrasonography had their EDD adjusted because of a discrepancy of more than 5 days between ultrasound dating and LMP dating . Estimated due dates were adjusted in only 10% of the women in the control group who had ultrasonography in the second trimester, which suggests that first-trimester ultrasound examination can improve the accuracy of the EDD, even when the first day of the LMP is known.

Existing definitions categorise preterm birth by clinical presentation, BW and GA. Determinants and consequences of discrepancies in menstrual and ultrasonographic gestational age estimates. Model training was performed on an NVIDIA Tesla V100, and the optimised convergence of each GA estimation model was found in approximately 48 h per single standard plane model. The convergence and fine-tuning of a multiple standard plane model using the single standard plane models as pre-trained weights took a further 12 h, with images augmented in a process described elsewhere19. However, after training and convergence, inference with new images could be performed on an average of 39 (95% CI; 35 to 43) frames/s, which is fast enough for inference during real-time ultrasound scanning.

Association between amniotic fluid evaluation and fetal biometry: a prospective French “Flash” study

Although their outcomes are better than outcomes of preterm infants with gestational ages of less than 32 or 33 weeks, late preterm infants remain vulnerable to the complications of prematurity. Despite a relative lack of information regarding long-term outcomes, retrospective studies of children with cerebral palsy report that 16 percent to 20 percent were born between 32 and 36 weeks gestation (Hagberg et al., 1996; MacGillivray and Campbell, 1995). When LMP is used to determine gestational age, 40 weeks is added to the LMP to calculate the estimated date of confinement (EDC; which is also referred to as the estimated due date); that is, the day when the infant is due to be born (Figure 2-2). This convention of defining gestational age in terms of LMP has been incorporated into the definition of gestational age and used for many years. For women who have used ARTs, EDC is determined from the date of egg retrieval , but gestational age is expressed by use of the conventional definition . Although it is confusing, gestational age as arbitrarily defined includes an estimated 2 weeks before the embryo is fertilized for the sake of convention and based on the historical use of the term gestational age.

Verhoeff F.H., Milligan P., Brabin B.J., Mlanga S., Nakoma V. Gestational age assessment by nurses in a developing country using the Ballard method, external criteria only. Breart G., Blondel B., Tuppin P., Grandjean H., Kaminski M. Did preterm deliveries continue to decrease in France in the 1980. Chauhan K.P. Assessment of symphysio-fundal height and its implication during antenatal period. US Department of Health and Human Services Public Health Service Centers for Disease Control and Prevention; 1994. Wilcox A.J. On the importance – and the unimportance – of birthweight. Segal S., Gemer O., Yaniv M. The outcome of pregnancy in an immigrant Ethiopian population in Israel.